ANEMIA : A quantitative deficiency of the hemoglobin, often accompanied by a reduced number of red blood cells and causing pallor, weakness, and breathlessness.

BIOLOGICS : Any substance, as a serum or vaccine, derived from animal products or other biological sources and used to treat or prevent disease.

CONDITIONALLY APPROVED PRODUCTS : Products which have received a conditional license from the United States Department of Agriculture after demonstrating reasonable expectations of efficacy, safety purity and potency.

CYTOKINE : Any of several non-antibody proteins, such as lymphokines, that are released by a cell population on contact with a specific antigen and act as intercellular mediators, as in the generation of an immune response.

EFFICACY : The ability of a drug or biologic to produce the desired therapeutic effect.

FELINE IMMUNODEFICIENCY VIRUS (FIV) : Also known as Feline Aids, is a retrovirus that may result in severe immune suppression in cats. FIV can attack the immune system of cats, much like the human immunodeficiency virus (HIV) can attack the immune system of human beings.

FELINE LEUKEMIA VIRUS (FeLV): A retrovirus that may cause severe immune suppression, anemia, and result in increased risk of other infections. FeLV and FIV infections are two of the most common feline diseases worldwide.

GRANULOCYTOPENIA : Reduction in the number of granular leukocytes in the blood, such as neutrophils, eosinophils, and basophils.

IMMUNE RESPONSE : An integrated bodily response to an antigen, especially one mediated by lymphocytes and involving recognition of antigens by specific antibodies or previously sensitized lymphocytes.

IMMUNE SUPPRESSION : Causing the immune system to become compromised or suppressed to the extent that an adequate response to pathogens, cancer, or inflammation is reduced.

Immunodeficiency virus : A virus that induces state in which the body’s immune system’s ability to fight infectious disease is compromised or entirely absent.

IMMUNOMODULATOR : Typically a biological product which produces an immune response, usually to modify an immune response or stimulate an immune response.

INTERLEUKIN : Interleukins are a set of cytokines which act as cell signals and often help elicit and direct immune responses.

LEUKEMIA : Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs and which is usually accompanied by anemia, impaired blood clotting, and enlargement of the lymph nodes, liver, and spleen.

LTCI : Lymphocyte T-Cell Immunomodulator, an immune modulating protein derived from a specialized thymic epithelial cell line.

LYOPHILIZED PRODUCT : A product which has been freeze dried, often to increase the shelf life of biologics.

LYMPHOCYTE : A white blood cell that plays a central role in immune responses to infections and cancer.

LYMPHOCYTE T-CELL IMMUNOMODULATOR : Lymphocyte T-Cell Immunomodulator, an immune modulating protein derived from a specialized thymic epithelial cell line.

Lymphoma : A type of cancer that originates in lymphocytes. It account for about five percent of all cases of cancer in the United States.

LYMPHOPENIA : A reduction in the number of lymphocytes within the blood.

RETROVIRUS : Enveloped viruses possessing an RNA genome, and replicate via a DNA intermediate. Retroviruses rely on the enzyme reverse transcriptase to perform the reverse transcription of its genome from RNA into DNA, which can then be integrated into the host’s genome with an integrase enzyme. The virus then replicates as part of the cell’s DNA.

SEPSIS : The presence of pathogenic organisms or their toxins in the blood or tissues.

T-HELPER CELLS : A class of lymphocytes which direct and coordinate the immune response.
Thrombocytopenia : The presence of relatively few platelets in blood. Decreased platelet counts can be due to a many different disease processes.

Lymphocyte T-Cell Immunomodulator (LTCI) is an conditionally approved treatment aid* for cats infected with Feline Leukemia Virus (FeLV) and/ or Feline Immunodeficiency Virus (FIV) and the associated symptoms of lymphopenia, opportunistic infection, anemia, granulocytopenia, and thrombocytopenia. LTCI is an immune regulating protein that is a potent regulator of CD4 development , function including lymphocyte and including increased interleukin-2 production.